Q: Which of the following equations correctly represents the process of gluconeogenesis stimulated by cortisol?

$$\text{Amino acids} + \text{Fatty acids} \rightarrow \text{Glucose}$$

Question 1

Which of the following best describes the difference between endocrine, paracrine, and autocrine signaling pathways?

Accepted Answer

Endocrine signals are secreted into the blood to affect distant targets, paracrine signals affect nearby but different types of cells, and autocrine signals affect the same cell or cell type that secreted them.

Question 2

A patient presents with muscle weakness, hypertension, and hypernatremia. Which adrenal hormone is most likely being hypersecreted?

Accepted Answer

Aldosterone

Question 3

Which hormone is primarily responsible for increasing blood calcium levels, and what is its main target tissue?

Accepted Answer

Parathyroid hormone; bone osteoclasts

Question 4

Which of the following is a correct statement about steroid hormones?

Accepted Answer

They are generally hydrophobic and bind to intracellular receptors in the cytosol or nucleus.

Question 5

A patient with Graves’ disease is likely to have which of the following laboratory findings?

Accepted Answer

Decreased TSH and elevated T3/T4

Question 6

Which hormone is secreted by the heart in response to increased blood volume, and what is its effect on blood pressure?

Accepted Answer

Atrial natriuretic peptide (ANP); decreases blood pressure

Question 7

Which of the following equations correctly represents the process of gluconeogenesis stimulated by cortisol?

Accepted Answer

$$	ext{Amino acids} + 	ext{Fatty acids} ightarrow 	ext{Glucose}$$

Question 8

A patient with Addison’s disease is at risk for which of the following due to hyposecretion of both cortisol and aldosterone?

Accepted Answer

Adrenal crisis with fluid, electrolyte, and acid-base imbalances

Question 9

Which hormone is released by beta cells of the pancreas and what is its primary effect?

Accepted Answer

Insulin; decreases blood glucose by promoting uptake and storage

Question 10

Which feedback loop best describes the regulation of thyroid hormone production?

Accepted Answer

Negative feedback loop involving TRH and TSH

Question 11

A patient with type I diabetes mellitus is likely to experience which of the following symptoms due to lack of insulin?

Accepted Answer

Hyperglycemia, polyuria, and polydipsia

Question 12

Which hormone is secreted by the kidneys in response to low blood oxygen, and what is its effect?

Accepted Answer

Erythropoietin; stimulates erythrocyte production

Question 13

Which of the following is a synergistic hormone interaction?

Accepted Answer

Two hormones act on the same target cell to exert the same effect, producing a greater response than either alone

Question 14

Which hormone is produced by adipose tissue and acts on the hypothalamus to induce satiety?

Accepted Answer

Leptin

Question 15

Which of the following best explains why oral growth hormone supplements are ineffective?

Accepted Answer

Growth hormone is a protein hormone and is destroyed by stomach acid and enzymes.

Question 16

Which hormone is secreted by the pineal gland and what is its primary function?

Accepted Answer

Melatonin; regulates sleep-wake cycles

Question 17

Which equation best represents the effect of insulin on blood glucose?

Accepted Answer

$$	ext{Glucose}_{	ext{blood}} ightarrow 	ext{Glycogen}_{	ext{liver}}$$

Question 18

Which hormone is secreted by the thymus and what is its role?

Accepted Answer

Thymosin; assists in T lymphocyte maturation

Question 19

Which of the following is a primary effect of estrogen in females?

Accepted Answer

Stimulates development of secondary sex characteristics and regulates menstrual cycle

Question 20

During exercise, which hormones are secreted to increase metabolic rate and provide metabolic fuels?

Accepted Answer

Catecholamines and glucagon

The Endocrine System: Overview and Signaling Pathways

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