Question 1

Which of the following fatty acids is the precursor to the eicosanoids?

Accepted Answer

Arachidonic acid

Question 2

Eicosanoids are lipids derived from which type of fatty acid?

Accepted Answer

Polyunsaturated fatty acids

Question 3

Which of the following is NOT a class of eicosanoids?

Accepted Answer

Steroids

Question 4

What is the main function of thromboxane A2 in the body?

Accepted Answer

Promotes blood clotting

Question 5

Which of the following statements about eicosanoids is TRUE?

Accepted Answer

All eicosanoids contain free conjugated double bonds.

Question 6

Which enzyme is responsible for converting arachidonic acid to prostaglandins?

Accepted Answer

Cyclooxygenase

Question 7

Non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin lower body temperature by blocking production of which eicosanoid?

Accepted Answer

Prostaglandins

Question 8

Which of the following is a function of leukotrienes?

Accepted Answer

Induce strong smooth muscle contraction in lungs

Question 9

Prostaglandins are local regulators whose chemical structure is derived from:

Accepted Answer

Fatty acids

Question 10

Which of the following best describes the structure of thromboxanes?

Accepted Answer

They have a six-membered ring with an ether.

Question 11

Which of the following reactions is catalyzed by cyclooxygenase (COX)?

Accepted Answer

Conversion of arachidonic acid to prostaglandin E2

Question 12

Which of the following eicosanoids is most directly involved in triggering asthma attacks?

Accepted Answer

Leukotriene D4

Question 13

Which of the following statements about prostaglandins is FALSE?

Accepted Answer

They contain a six-membered ring with an ether.

Question 14

A patient is prescribed aspirin to reduce fever. Which biochemical pathway is most directly inhibited?

Accepted Answer

Cyclooxygenase pathway

Question 15

Which of the following is a common feature of all eicosanoids?

Accepted Answer

They contain conjugated double bonds.

Question 16

Which of the following best explains why NSAIDs can cause stomach ulcers?

Accepted Answer

NSAIDs inhibit prostaglandin synthesis, reducing protective mucus in the stomach.

Question 17

Which of the following equations correctly represents the conversion of arachidonic acid to prostaglandin E2?

Accepted Answer

$$\mathrm{Arachidonic\ Acid} \xrightarrow{COX} \mathrm{Prostaglandin\ E2}$$

Question 18

Which eicosanoid is most directly involved in the formation of blood clots?

Accepted Answer

Thromboxane A2

Question 19

Which of the following is a correct statement about leukotrienes?

Accepted Answer

They induce strong muscle contraction in the lungs.

Question 20

Which of the following is the correct chemical structure for the precursor of eicosanoids?

Accepted Answer

$$\mathrm{C$$_{20}$$H_{32}O_2$}$$

Eicosanoids: Structure, Function, and Biochemical Significance

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