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General Biology: Foundations, Chemistry of Life, and Biological Molecules

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Scientific Inquiry and Experimental Design

Overview of Scientific Inquiry

Scientific inquiry is the systematic process by which scientists investigate natural phenomena, develop explanations, and test hypotheses. It involves observation, experimentation, and communication of results.

  • Observation: Using senses to gather information about the natural world.

  • Inference: Logical interpretation based on observations.

  • Hypothesis: A testable, falsifiable explanation for an observation.

  • Prediction: A specific outcome expected if a hypothesis is true.

  • Experiment: A procedure to test a hypothesis under controlled conditions.

  • Variable: Any factor that can change in an experiment.

Types of Variables

  • Independent Variable: The factor changed by the experimenter (manipulated variable).

  • Dependent Variable: The factor measured in the experiment (responding variable).

  • Controlled Variables (Constants): Factors kept the same in all groups to ensure a fair test.

Experimental Groups

Group

Description

Control Group

Does not receive the experimental treatment; used as a baseline.

Experimental Group

Receives the independent variable (treatment).

Blind and Double-Blind Experiments

Type

Description

Blind

Subjects do not know which group they are in.

Double-Blind

Both subjects and experimenters do not know group assignments.

Outcomes of Experiments

  • Support the Hypothesis: Data is consistent with the hypothesis (not 'proven').

  • Refute the Hypothesis: Data contradicts the hypothesis, leading to revision or new hypotheses.

  • Inconclusive: More data or a different design is needed.

Distinguishing Good Science from Pseudoscience

  • Good Science: Based on empirical evidence and falsifiable hypotheses.

  • Pseudoscience: Lacks empirical support and proper methodology.

Key Scientific Terms

  • Theory: A well-supported, broad explanation of natural events (e.g., evolution).

  • Law: A statement describing consistent, universal patterns in nature.

  • Fact: An observation confirmed repeatedly.

  • Bias: Personal preference or opinion that may influence interpretation.

  • Qualitative Data: Descriptions (e.g., color, texture).

  • Quantitative Data: Numerical measurements.

Properties and Themes of Life

8 Properties of Life

  • Order: Organized structure (cells, organs).

  • Reproduction: Ability to produce offspring.

  • Growth and Development: Change and increase in size over time.

  • Energy Processing: Use of energy (e.g., food, photosynthesis).

  • Regulation: Maintenance of homeostasis (e.g., body temperature).

  • Evolutionary Adaptation: Change over generations.

  • Cells: All life is made of one or more cells.

  • Response to Environment: Reacting to stimuli.

5 Unifying Themes of Life

  • Evolution: Core theme; explains unity and diversity.

  • Structure and Function: Form fits function (e.g., wings for flight).

  • Information Flow: DNA → RNA → proteins.

  • Energy and Matter Pathways: Energy flows, matter cycles (e.g., food webs, water cycles).

  • Interactions: Organisms interact with each other and their environment.

Levels of Biological Organization

Level

Description

Biosphere

All ecosystems on Earth

Ecosystem

Living and non-living in one area

Community

All living organisms in an area

Population

One species in one area

Organism

Individual living thing

Organ System

Group of organs working together

Organ

Structure with specific functions

Tissue

Group of similar cells

Cell

Basic unit of life

Chapter 2: Chemistry of Life

Basic Chemical Concepts

  • Matter: Anything that takes up space and has mass.

  • Mass: How much "stuff" is in something.

  • Atom: The smallest unit of an element; building block of matter.

  • Element: One kind of atom (e.g., oxygen).

  • Compound: Two or more elements chemically bonded together.

Elements Essential for Life

  • C-H-O-N: Carbon, Hydrogen, Oxygen, Nitrogen – the four elements that make up most living matter.

Comparing Atoms, Elements, Compounds, Matter, and Mass

Term

Description

Atom

One tiny piece of matter

Element

A bunch of the same kind of atom

Compound

Different atoms bonded together

Matter

Anything with mass and volume

Mass

How much matter something has

Subatomic Particles

Part

Charge

Location

Proton

+1

In the nucleus

Neutron

0

In the nucleus

Electron

-1

Outside the nucleus

Atomic Number, Mass Number, and Isotopes

  • Atomic Number: Number of protons in an atom (found on the periodic table).

  • Mass Number: Number of protons plus neutrons.

  • Atomic Mass: Average mass of all isotopes (decimal number on the table).

  • Isotopes: Atoms of the same element with different numbers of neutrons (e.g., Carbon-12 vs. Carbon-14).

Chemical Bonds

Bond Type

Atoms Do What?

Between What?

Covalent

Share electrons

2 nonmetals (e.g., H2O)

Ionic

Give/take electrons

Metal + nonmetal (e.g., NaCl)

Hydrogen

Weak attraction

Between water molecules

Properties of Water (Due to Hydrogen Bonds)

  • Cohesion: Water sticks to water.

  • Adhesion: Water sticks to other substances.

  • High Specific Heat: Water resists temperature change.

  • Ice Floats: Ice is less dense than liquid water.

Chapter 3: Biological Molecules

Monomers and Polymers

  • Monomer: One building block (e.g., glucose).

  • Polymer: Many monomers linked together (e.g., starch).

  • Dehydration Synthesis: Water is removed to build polymers.

  • Hydrolysis: Water is added to break polymers apart.

Organic Compounds and Carbon

  • Carbon: Can form 4 covalent bonds, allowing for complex molecules.

  • Main atom in living things: Carbon's bonding ability makes it central to life.

Types of Biological Molecules

  • Carbohydrates: Sugars and starches; main energy source.

  • Lipids: Fats and oils; energy storage and cell membranes.

  • Proteins: Made of amino acids; perform most cellular functions.

  • Nucleic Acids: DNA and RNA; store genetic information.

Carbohydrates: Monosaccharides, Disaccharides, Polysaccharides

  • Monosaccharide: Single sugar molecule (e.g., glucose, fructose, galactose).

  • Disaccharide: Two sugars linked (e.g., sucrose = glucose + fructose).

  • Polysaccharide: Many sugars linked (e.g., starch, glycogen, cellulose, chitin).

Examples of Carbohydrates

Type

Examples

Monosaccharide

Glucose, Fructose, Galactose

Disaccharide

Sucrose (Glucose + Fructose), Maltose (Glucose + Glucose), Lactose (Glucose + Galactose)

Polysaccharide

Starch (plants), Glycogen (animals), Cellulose (plants), Chitin (fungi/arthropods)

Lipids

  • Fats: Made of glycerol and fatty acids; store energy.

  • Steroids: Ring-shaped lipids (e.g., cholesterol, hormones).

Proteins

  • Made of amino acids: 20 different types.

  • Functions: Build body parts, enzymes, hormones, etc.

*Additional info: Some explanations and examples were expanded for clarity and completeness based on standard biology curriculum.*

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