Scelta multipla
In DNA replication, which enzyme unwinds ("unzips") the double helix by breaking hydrogen bonds to prepare the DNA template strands for replication?
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8. DNA Replication
Overview of DNA Replication
Scelta multipla
During DNA replication, which enzyme initiates DNA synthesis by creating a short RNA segment (primer) that provides a free group for DNA polymerase?
A
Primase
B
DNA ligase
C
DNA polymerase III
D
Helicase
Guida verificata passo dopo passo1
Understand the role of each enzyme listed in the problem during DNA replication.
Recall that DNA polymerase cannot start DNA synthesis on its own because it requires a free 3\' OH group to add nucleotides.
Identify the enzyme that synthesizes a short RNA primer to provide this free 3\' OH group; this enzyme is called primase.
Recognize that DNA ligase is responsible for joining Okazaki fragments, not initiating synthesis.
Note that helicase unwinds the DNA double helix, and DNA polymerase III extends the DNA strand but does not initiate it.
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