Question 1

Which of the following statements best describes a chiral molecule?

Accepted Answer

It is not superimposable on its mirror image and contains a carbon atom bonded to four unique groups.

Question 2

Which of the following molecules is achiral?

Accepted Answer

A molecule with a plane of symmetry and at least one carbon atom bonded to two identical groups.

Question 3

What is the term for optical isomers that are non-superimposable mirror images of each other?

Accepted Answer

Enantiomers

Question 4

A carbon atom is considered a chiral center if it is bonded to:

Accepted Answer

Four unique groups

Question 5

Which of the following molecules can rotate plane-polarized light?

Accepted Answer

A chiral molecule

Question 6

When drawing enantiomers using method 1, what is the correct procedure?

Accepted Answer

Draw the image the molecule 'sees' in the mirror.

Question 7

Which of the following is true about enantiomers?

Accepted Answer

They have identical physical properties except for their interaction with plane-polarized light.

Question 8

A student is given a molecule with the following structure: $$\mathrm{HOCH_2CH(OH)CH_3COOH}. $$How many chiral centers does this molecule have?

Accepted Answer

1

Question 9

Which of the following best explains why thalidomide caused birth defects when administered as a racemic mixture?

Accepted Answer

One enantiomer was therapeutic, while the other was teratogenic.

Question 10

Which method involves changing solid wedges to dashed wedges and vice versa at the chiral center to draw an enantiomer?

Accepted Answer

Method 2

Question 11

A molecule has two chiral centers. How many possible stereoisomers can it have?

Accepted Answer

$$4$$

Question 12

Which of the following is NOT a property of chiral molecules?

Accepted Answer

They always contain a plane of symmetry.

Question 13

Which of the following molecules is most likely to be optically inactive?

Accepted Answer

A molecule with a plane of symmetry

Question 14

If a molecule has the formula $$\mathrm{C_4H_{10}}$$ and contains no chiral centers, what is its relationship to plane-polarized light?

Accepted Answer

It will not rotate plane-polarized light.

Question 15

Which of the following is a correct definition of a chiral center?

Accepted Answer

A carbon atom bonded to four different groups.

Question 16

Which of the following is true about the optical activity of enantiomers?

Accepted Answer

Enantiomers rotate plane-polarized light in equal and opposite directions.

Question 17

A molecule with the structure $$\mathrm{NH_2CH_2CH_3} is$$:

Accepted Answer

Achiral

Question 18

Which of the following is a correct application of the concept of chirality in pharmaceuticals?

Accepted Answer

Chiral drugs may have enantiomers with different biological activities.

Question 19

Which of the following best describes the relationship between a molecule and its enantiomer?

Accepted Answer

They have identical chemical and physical properties except for their interaction with plane-polarized light.

Question 20

Which of the following is the correct way to identify a chiral center in a molecule?

Accepted Answer

Look for a carbon atom bonded to four unique groups.

Chirality and Enantiomers in GOB Chemistry: Study Notes

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