Question 1

Which type of enzyme inhibition results in both $$V_{max}$$ and $$K_m$$ being lowered by the same ratio?

Accepted Answer

Uncompetitive inhibition

Question 2

A patient is given a drug that binds to the enzyme-substrate complex but not to the free enzyme. What type of inhibition is this?

Accepted Answer

Uncompetitive inhibition

Question 3

Which equation describes the Michaelis constant ($$K_m) $$for an enzyme-catalyzed reaction?

Accepted Answer

$$K_m = \frac{V_{max}}{2}$$

Question 4

Which regulatory mechanism involves the addition or removal of a phosphate group to change enzyme activity?

Accepted Answer

Covalent modification

Question 5

A digestive enzyme is synthesized in an inactive form and activated by removal of a protein segment. What is this inactive form called?

Accepted Answer

Zymogen

Question 6

Which statement about fat-soluble vitamins is correct?

Accepted Answer

Fat-soluble vitamins are primarily stored in the liver.

Question 7

Which vitamin is ingested in its provitamin form and is essential for vision and cell growth?

Accepted Answer

Vitamin A (retinol)

Question 8

Which water-soluble vitamin is required for collagen synthesis and acts as an antioxidant?

Accepted Answer

Vitamin C (ascorbic acid)

Question 9

Which coenzyme is derived from niacin and is involved in oxidation-reduction reactions?

Accepted Answer

Nicotinamide adenine dinucleotide (NAD+)

Question 10

A blood test shows elevated levels of creatine kinase (CK) and lactate dehydrogenase (LDH). What does this most likely indicate?

Accepted Answer

Heart attack

Question 11

The lateral flow assay for COVID-19 detection uses which class of proteins to bind to the spike protein of SARS-CoV2?

Accepted Answer

Protective proteins (antibodies)

Question 12

Which vitamin is required for the formation of prothrombin and is essential for blood clotting?

Accepted Answer

Vitamin K

Question 13

Which regulatory mechanism involves a product of a metabolic pathway inhibiting the first enzyme in the pathway?

Accepted Answer

Negative feedback control

Question 14

Which statement best describes a coenzyme?

Accepted Answer

A coenzyme is an organic compound required for catalysis.

Question 15

Which vitamin deficiency is most likely to cause neural tube defects in newborns?

Accepted Answer

Vitamin B9 (folic acid)

Question 16

Which enzyme regulation mechanism is most likely to be triggered by the addition of a phosphate group to a serine residue?

Accepted Answer

Covalent modification

Question 17

Which vitamin is destroyed by light but not by normal cooking temperatures?

Accepted Answer

Vitamin B2 (riboflavin)

Question 18

Which statement about water-soluble vitamins is correct?

Accepted Answer

They form coenzymes and are not stored in the body.

Question 19

Which vitamin acts as a carrier of acetyl groups into the TCA cycle?

Accepted Answer

Vitamin B5 (pantothenic acid)

Question 20

Which statement about enzyme isozymes is correct?

Accepted Answer

Isozymes are tissue-specific forms of the same enzyme that catalyze the same reaction.

Lecture 11

Guida di studio - Domande di pratica