026e7687-why-does-the-incorporation-of-a-dideoxynucleotide-into-a-growing-dna-st

Question

Why does the incorporation of a dideoxynucleotide into a growing DNA strand result in chain termination?

Accepted Answer

Dideoxynucleotides lack a 3' hydroxyl group, preventing further extension

Answer

They contain a reactive sulfur group that cleaves the DNA

Answer

Dideoxynucleotides have an extra phosphate group that blocks elongation

Answer

They form unstable bonds with adjacent nucleotides