Ch. 21 - Microbial Diseases of the Skin and Eyes

Tortora - Microbiology: An Introduction 14th Edition

Tortora14th EditionMicrobiology: An IntroductionISBN: 9780138200398Non è quello che usi tu?Cambia libro di testo

Tortora 14th Edition

Ch. 21 - Microbial Diseases of the Skin and Eyes

Problema 1

Capitolo 17, Problema 1

Discuss the usual mode of entry of bacteria into the skin. Compare bacterial skin infections with infections caused by fungi and viruses with respect to mode of entry.

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Begin by explaining that the usual mode of entry of bacteria into the skin is through breaches or disruptions in the skin's protective barrier, such as cuts, abrasions, insect bites, or other injuries that compromise the integrity of the epidermis.

Describe that bacteria can also enter through hair follicles or sweat gland ducts, which serve as natural openings in the skin, allowing colonization and infection if the immune defenses are overcome.

For fungal infections, explain that fungi typically enter through direct contact with contaminated surfaces or environments, often exploiting moist, warm areas of the skin where the barrier may be weakened, but they generally do not require deep skin breaks to infect.

Discuss viral skin infections by noting that viruses often enter through microabrasions or small, sometimes invisible, breaks in the skin or mucous membranes, and some viruses can infect skin cells directly without the need for significant injury, often spreading via direct contact or respiratory droplets.

Conclude by comparing these modes of entry: bacterial infections usually require a physical breach in the skin barrier, fungal infections often exploit moist environments and superficial skin layers, and viral infections can enter through minor skin disruptions or mucosal surfaces, highlighting differences in their pathogenesis and infection routes.

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Mode of Entry of Bacteria into the Skin

Bacteria typically enter the skin through breaches such as cuts, abrasions, or insect bites, exploiting disruptions in the skin barrier. Intact skin is generally resistant due to its protective layers and antimicrobial secretions. Understanding these entry points is crucial for grasping how bacterial infections initiate.

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Entry & Uncoating by Endocytosis

Bacterial Skin Infections

Bacterial skin infections often arise from direct invasion through damaged skin, leading to localized conditions like impetigo or cellulitis. These infections usually involve extracellular bacteria that multiply in superficial or deeper skin layers, triggering inflammation and immune responses.

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Intro to Bacterial Pathogenesis

Fungal and Viral Skin Infections: Modes of Entry

Fungi commonly invade through minor skin trauma or by colonizing keratinized layers, thriving in moist environments, while viruses often enter via skin microabrasions or through mucous membranes. Unlike bacteria, viruses require host cells to replicate, and fungi digest keratin to penetrate the skin.

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Persistent Viral Infections

Pratica correlata

Domanda del libro di testo

A 6-year old girl was taken to the physician for evaluation of a slowly growing bump on the back of her head. The bump was a raised, scaling lesion 4 cm in diameter. A fungal culture of material from the lesion was positive for a fungus with numerous conidia.

The girl’s disease was

a. Rubella.

b. Candidiasis.

c. Dermatomycosis.

d. A cold sore.

e. None of the above.

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Domanda del libro di testo

What bacteria are identified by a positive coagulase test? What bacteria are characterized as group A beta-hemolytic?

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