Question 1

Which of the following best defines binge drinking for men according to the National Institute on Alcohol Abuse and Alcoholism (NIAAA)?

Accepted Answer

Consuming 5 or more drinks in about 2 hours, raising blood alcohol concentration (BAC) to $$\geq 0.08\ \mathrm{g/dL}$$

Question 2

A patient presents with confusion, ataxia, and nystagmus. They have a history of chronic alcohol use. Which nutritional deficiency is most likely responsible for these symptoms?

Accepted Answer

Vitamin B1 (thiamine) deficiency

Question 3

Which of the following is a first-line pharmacological treatment for alcohol withdrawal syndrome?

Accepted Answer

Benzodiazepines (e.g., diazepam, lorazepam)

Question 4

A patient is prescribed disulfiram for alcohol dependence. What is the primary mechanism of action of disulfiram?

Accepted Answer

Prevents breakdown of alcohol, causing accumulation of acetaldehyde and unpleasant physical reactions

Question 5

Which of the following blood alcohol levels (BAL) is most likely associated with coma and risk of death due to overdose?

Accepted Answer

$$\mathrm{BAL} \u003e 300\ \mathrm{mg/dL}$$

Question 6

A patient with alcohol use disorder is started on naltrexone. Which of the following is a contraindication for naltrexone therapy?

Accepted Answer

Active opioid use or liver failure

Question 7

Which of the following is a clinical manifestation of chronic alcohol use?

Accepted Answer

Pancreatitis and liver disease

Question 8

A patient is experiencing agitation, tremor, and hypertension 12 hours after their last drink. What is the most likely diagnosis?

Accepted Answer

Alcohol withdrawal syndrome

Question 9

Which of the following statements about acamprosate is correct?

Accepted Answer

It requires abstinence before starting, typically 5 days after last drink

Question 10

A patient with a history of alcohol use disorder presents with amnesia, confabulation, and inability to form new memories. Which syndrome is most likely?

Accepted Answer

Korsakoff syndrome

Question 11

Which of the following is a key goal in the management of alcohol withdrawal delirium (delirium tremens)?

Accepted Answer

Avoiding DTs and seizures

Question 12

Which neurotransmitter is most affected by alcohol’s CNS depressant effects?

Accepted Answer

Gamma-aminobutyric acid (GABA)

Question 13

A patient is being assessed for alcohol withdrawal using the CIWA-Ar scale. Which of the following is the primary purpose of this assessment?

Accepted Answer

To assess severity of withdrawal symptoms and guide treatment

Question 14

Which of the following is a recommended nursing intervention for a patient experiencing a severe disulfiram reaction?

Accepted Answer

Administer oxygen, monitor ECG and serum potassium, and provide supportive measures

Question 15

Which of the following is true regarding the equivalence of standard alcoholic drinks?

Accepted Answer

12 ounces of regular beer contains about 5% alcohol

Question 16

A patient with alcohol use disorder is started on naltrexone. Which laboratory test must be monitored regularly during therapy?

Accepted Answer

Liver function tests (LFTs)

Question 17

Which of the following is a common side effect of acamprosate?

Accepted Answer

Diarrhea and anxiety

Question 18

A patient with chronic alcohol use is at risk for which of the following nutritional deficiencies?

Accepted Answer

Thiamine (Vitamin B1) deficiency

Question 19

Which of the following is a recommended patient teaching point for someone taking disulfiram?

Accepted Answer

Avoid all products containing alcohol, including medications and mouthwash

Question 20

A patient with alcohol use disorder is being considered for naltrexone therapy. Which of the following statements is correct?

Accepted Answer

Naltrexone is not addictive and does not cause withdrawal symptoms

Alcohol Abuse: Pathophysiology, Clinical Manifestations, and Treatment in Nutrition

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