EAS:Retrosynthesis

19. Reactions of Aromatics: EAS and Beyond / EAS – Proposing Aromatic Synthesis / Problema 4

Problema 4

Illustrate three different strategies by which the reaction given below can be carried out.

First strategy for EAS retrosynthesis with LiAlH4 and H+.

Second strategy for EAS retrosynthesis using HSCH2CH2CH2SH.

Third strategy for EAS retrosynthesis with HSCH2CH2CH2SH and NaBH4.

Alternative strategy for EAS retrosynthesis using LiAlH4 and PCC.