Question 1

Which of the following best describes the two major products of triacylglycerol digestion in the small intestine?

Accepted Answer

Fatty acids and monoacylglycerols

Question 2

What is the correct sequence for the four reactions of the $$\beta-$$oxidation pathway in terms of functional group changes?

Accepted Answer

Alkane, alkene, 2° alcohol, ketone

Question 3

Which of the following statements about the energy yield from the complete oxidation of one molecule of palmitic acid ($$C_{16}) is $$correct?

Accepted Answer

$$106$$ ATP are produced

Question 4

Which molecule is the starting material for ketogenesis?

Accepted Answer

Acetyl CoA

Question 5

Which of the following is NOT classified as a ketone body?

Accepted Answer

Malonyl ACP

Question 6

Which of the following is a correct ordering of cholesterol biosynthesis intermediates?

Accepted Answer

Isopentenyl pyrophosphate, squalene, lanosterol

Question 7

Which of the following statements about the use of fats in the human body is correct?

Accepted Answer

Cardiac muscle prefers fatty acids for energy, especially during starvation

Question 8

Which of the following processes requires molecular $$O_2 as a $$reactant?

Accepted Answer

Electron transport chain

Question 9

Which enzyme is required for processing unsaturated fatty acids through the $$\beta-$$oxidation pathway?

Accepted Answer

An isomerase to change a cis $$\$$Delta^3$$ double bond to a trans $$\$$Delta^2$$ bond

Question 10

How many cycles of the $$\beta-$$oxidation pathway are required to completely degrade a $$C_{18}$$ fatty acid?

Accepted Answer

$$8$$

Question 11

Which of the following is the carrier of the 'two carbon units' used in biosynthesis of a fatty acid?

Accepted Answer

Malonyl ACP

Question 12

Which of the following statements about lipoproteins is correct?

Accepted Answer

They transport triacylglycerols from intestinal cells to the bloodstream

Question 13

Which of the following is an intermediate in the conversion of glycerol to dihydroxyacetone phosphate?

Accepted Answer

Glycerol-3-phosphate

Question 14

Which of the following statements about the biosynthesis of cholesterol is correct?

Accepted Answer

It involves the condensation of six isoprene units to form squalene

Question 15

Which of the following is the correct sequence of reactions in the $$\beta-$$oxidation pathway?

Accepted Answer

Dehydrogenation, hydration, dehydrogenation, thiolysis

Question 16

Which of the following statements about the regulation of fatty acid biosynthesis is correct?

Accepted Answer

Malonyl CoA inhibits carnitine acyltransferase I, preventing fatty acid entry into mitochondria

Question 17

Which of the following statements about the fate of acetyl CoA in the liver during fasting is correct?

Accepted Answer

It is converted to ketone bodies for export to other tissues

Question 18

Which of the following is a true statement about the ATP yield from fatty acid oxidation compared to carbohydrate oxidation?

Accepted Answer

Fatty acids produce more than twice as much ATP per gram as carbohydrates

Question 19

Which of the following is a correct statement about the fate of glycerol released during triacylglycerol hydrolysis?

Accepted Answer

It is converted to dihydroxyacetone phosphate and enters glycolysis

Question 20

Which of the following is the correct number of NADH molecules produced after 8 'turns' of the $$\beta-$$oxidation pathway?

Accepted Answer

$$8$$

Lipid Metabolism: Key Concepts and Pathways in Organic Chemistry

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