Question 1

Which of the following statements best describes a chiral molecule?

Accepted Answer

A molecule that is not superposable on its mirror image.

Question 2

Which of the following molecules would be expected to be achiral?

Accepted Answer

A molecule with a plane of symmetry.

Question 3

How many stereoisomers are possible for a molecule with three chiral centers?

Accepted Answer

$$2^3 = 8$

Question 4

Which of the following best describes enantiomers?

Accepted Answer

Stereoisomers that are nonsuperposable mirror images of each other.

Question 5

A molecule of 2-butanol has a chiral center. What is the relationship between its two enantiomers?

Accepted Answer

They have identical physical and chemical properties in an achiral environment.

Question 6

Which of the following is true about meso compounds?

Accepted Answer

They are achiral despite having chiral centers.

Question 7

What is the correct IUPAC name for a molecule with two chiral centers, both in the R configuration, and the structure of erythrose?

Accepted Answer

(2R,3R)-erythrose

Question 8

Which of the following statements about diastereomers is correct?

Accepted Answer

They are stereoisomers that are not mirror images of each other.

Question 9

Which of the following best describes the R, S system for naming chiral centers?

Accepted Answer

It assigns configuration based on the clockwise or counterclockwise arrangement of groups by priority.

Question 10

Which of the following molecules is most likely to be a meso compound?

Accepted Answer

cis-1,2-cyclopentanediol

Question 11

A molecule has the following groups attached to a central carbon: $$-Cl$$, $$-H$$, $$-CH_3$, -Br$. What is true about this carbon?

Accepted Answer

It is a chiral center.

Question 12

Which of the following is a correct application of the Cahn-Ingold-Prelog priority rules?

Accepted Answer

A $$-CH_2Cl$$ group has higher priority than a $$-CH_2CH_2CH_3$$ group.

Question 13

Which of the following statements about conformational isomers is correct?

Accepted Answer

They are isomers that differ by rotation about a single bond.

Question 14

Which of the following best describes atropisomers?

Accepted Answer

Enantiomers that differ due to hindered rotation and lack a chiral center.

Question 15

How many stereoisomers are possible for 3-methylcyclopentanol, which has two chiral centers?

Accepted Answer

$$2^2 = 4$

Question 16

Which of the following is true about the physical properties of enantiomers?

Accepted Answer

They have identical melting points and boiling points in an achiral environment.

Question 17

Which of the following is a correct Fischer projection for (R)-glyceraldehyde?

Accepted Answer

A Fischer projection with the $$-OH$$ group on the right.

Question 18

Which of the following best describes the relationship between cis- and trans-1,2-cyclopentanediol?

Accepted Answer

They are diastereomers.

Question 19

Which of the following statements about the stereoisomers of tartaric acid is correct?

Accepted Answer

The meso form is achiral and has a plane of symmetry.

Stereoisomerism and Chirality: Foundations and Applications

Guida di studio - Domande di pratica