describe-the-sequence-of-events-leading-to-the-activation-of-pi-3-kinase-and-its

Question

Describe the sequence of events leading to the activation of PI 3-kinase and its role in insulin signaling.

Accepted Answer

PI 3-kinase is activated by binding to phosphorylated tyrosine residues on IRS, converting PIP2 to PIP3.

Answer

PI 3-kinase is activated by insulin directly, converting PIP2 to PIP3.

Answer

PI 3-kinase is activated by glucose binding, converting PIP3 to PIP2.

Answer

PI 3-kinase is activated by binding to phosphorylated serine residues on IRS, converting PIP3 to PIP2.