what-is-a-reason-edman-degradation-is-limited-to-small-polypeptide-chains

Question

What is a reason Edman degradation is limited to small polypeptide chains?

Accepted Answer

The efficiency of the reaction decreases with larger chains.

Answer

Small chains are easier to handle in the lab.

Answer

The reagents are only effective on small peptides.

Answer

Larger chains cannot be isolated for sequencing.