in-a-protein-engineering-project-you-need-to-introduce-flexibility-into-an-alpha

Question

In a protein engineering project, you need to introduce flexibility into an alpha helix. Which amino acid would you choose and why?

Accepted Answer

Glycine, because its small size allows for more conformational freedom.

Answer

Tryptophan, because its bulkiness increases flexibility.

Answer

Proline, because it introduces a kink that increases flexibility.

Answer

Lysine, because its charge increases flexibility.