why-is-edman-degradation-preferred-over-mass-spectrometry-for-differentiating-is

Question

Why is Edman degradation preferred over mass spectrometry for differentiating isomeric amino acids like Leucine and Isoleucine?

Accepted Answer

Edman degradation can differentiate isomers based on their sequence, while mass spectrometry cannot.

Answer

Edman degradation is faster than mass spectrometry.

Answer

Edman degradation is less expensive than mass spectrometry.

Answer

Edman degradation requires less sample preparation than mass spectrometry.