why-does-the-reversal-of-pyruvate-kinases-action-in-glycolysis-require-two-steps

Question

Why does the reversal of pyruvate kinase's action in glycolysis require two steps in gluconeogenesis?

Accepted Answer

Pyruvate kinase's action is highly favorable and cannot be reversed in a single step.

Answer

Pyruvate kinase is inhibited by ATP.

Answer

Pyruvate kinase requires two different enzymes to function.

Answer

The reaction is too slow to be completed in one step.