How do noncompetitive inhibitors bind to enzymes compared to mixed inhibitors?

Noncompetitive inhibitors bind with different affinities to the free enzyme and the enzyme-substrate complex.

Noncompetitive inhibitors only bind to the enzyme-substrate complex.

Noncompetitive inhibitors bind with the same affinity to both the free enzyme and the enzyme-substrate complex.

Noncompetitive inhibitors only bind to the free enzyme.