how-does-the-structure-of-prpsc-differ-from-prpc-and-what-is-the-consequence-of-

Question

How does the structure of PrPSC differ from PrPC, and what is the consequence of this difference?

Accepted Answer

PrPSC has a beta-sheet rich structure, causing it to aggregate and convert PrPC into PrPSC.

Answer

PrPSC lacks a tertiary structure, preventing it from interacting with PrPC.

Answer

PrPSC is a smaller protein, allowing it to easily penetrate cell membranes.

Answer

PrPSC has an alpha-helix rich structure, making it more stable than PrPC.