what-is-the-impact-of-negative-cooperativity-on-substrate-binding-affinity-in-th

Question

What is the impact of negative cooperativity on substrate binding affinity in the sequential model?

Accepted Answer

It decreases the likelihood of neighboring subunits binding the substrate.

Answer

It has no impact on substrate binding affinity.

Answer

It increases the likelihood of neighboring subunits binding the substrate.

Answer

It only affects the R state.