analyze-the-effect-of-a-mutation-that-prevents-the-dissociation-of-the-g-protein

Question

Analyze the effect of a mutation that prevents the dissociation of the G protein alpha subunit from the beta gamma subunits. How would this affect the signaling pathway?

Accepted Answer

Adenylate cyclase would not be activated, preventing the conversion of ATP to cyclic AMP.

Answer

The GPCR would continuously activate the G protein without ligand binding.

Answer

Protein kinase A would be activated directly by the GPCR.

Answer

The signaling pathway would terminate prematurely.