how-might-the-presence-of-a-hydrophobic-pocket-in-a-protein-binding-site-affect-

Question

How might the presence of a hydrophobic pocket in a protein binding site affect ligand binding?

Accepted Answer

It would likely increase binding affinity for hydrophobic ligands.

Answer

It would likely increase binding affinity for hydrophilic ligands.

Answer

It would have no effect on ligand binding.

Answer

It would likely decrease binding affinity for hydrophobic ligands.