Guida verificata passo dopo passo
09:16
05:48Refer to the genetic coding dictionary to respond to the following:
A base-substitution mutation that altered the sequence shown in part (a) eliminated the synthesis of all but one polypeptide. The altered sequence is shown here:
5'-AUGCAUACCUAUGUGACCCUUGGA-3'
Determine why.
Define the process of transcription. Where does this process fit into the central dogma of molecular biology (DNA makes RNA makes protein)?
Messenger RNA molecules are very difficult to isolate in bacteria because they are rather quickly degraded in the cell. Can you suggest a reason why this occurs? Eukaryotic mRNAs are more stable and exist longer in the cell than do bacterial mRNAs. Is this an advantage or a disadvantage for a pancreatic cell making large quantities of insulin?
Most proteins have more leucine than histidine residues, but more histidine than tryptophan residues. Correlate the number of codons for these three amino acids with this information.
Write a paragraph describing the abbreviated chemical reactions that summarize RNA polymerase-directed transcription.
Describe the structure of RNA polymerase in bacteria. What is the core enzyme? What is the role of the σ subunit?
