Fructose 1,6-bisphosphate is a key intermediate in metabolism and the glycolysis pathway. Which of the following conditions and statements below is correct?

Fructose 1,6-bisphosphate is converted to pyruvate in the presence of oxygen through the enzyme hexokinase.

Fructose 1,6-bisphosphate converts to pyruvate only under anaerobic conditions without any additional steps.

Fructose 1,6-bisphosphate is converted to pyruvate through glycolysis, involving steps like the formation of glyceraldehyde-3-phosphate, 1,3-bisphosphoglycerate, and 3-phosphoglycerate.

The conversion of fructose 1,6-bisphosphate to pyruvate occurs directly through the enzyme phosphofructokinase-1 (PFK-1).