A pathogenic feature of Cryptococcus neoformans is _________.
a. production of destructive enzymes
b. production of a capsule
c. infection of immune cells
d. variation of surface antigens to avoid immune system recognition

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Understand the organism: Cryptococcus neoformans is a fungal pathogen known for causing infections, especially in immunocompromised individuals.

Recall key pathogenic features: One of the hallmark features of Cryptococcus neoformans is its ability to produce a polysaccharide capsule, which helps it evade the host immune system.

Analyze each option: (a) Production of destructive enzymes is common in some pathogens but not the primary feature here; (b) Production of a capsule is a well-known virulence factor for Cryptococcus neoformans; (c) Infection of immune cells is more typical of intracellular pathogens like some bacteria and parasites; (d) Variation of surface antigens is a strategy used by some pathogens like trypanosomes, but not characteristic of Cryptococcus neoformans.

Match the correct feature: Based on the above, the production of a capsule is the defining pathogenic feature of Cryptococcus neoformans.

Conclude that the correct answer corresponds to option (b) production of a capsule.

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