Fill in the table.

List the applicable hypersensitivities (type I, II, III, IV) as they relate to the description. Note, more than one type of hypersensitivity may be listed for a given description.

IgG antibodies can mediate type _________________hypersensitivities.

T cells mediate type _________________ hypersensitivities.

Type _________________ hypersensitivities may be generated in response to pharmaceutical drugs.

Type _________________ hypersensitivities may be associated with autoimmunity.

Type _________________ hypersensitivities require a sensitizing exposure.

IgE antibodies can mediate type _________________hypersensitivities.

Which patient would be the most likely to benefit from desensitization immunotherapy?

a. A person suffering from serum sickness

b. A person at risk for HDN during pregnancy

c. A person with an allergy to pollen

d. A transplant patient

e. An asthmatic patient

Which of the following is the most suggestive of an anaphylactic reaction? (NCLEX/HESI/TEAS)

a. Sudden fever

b. A localized rash

c. Nasal congestion

d. Hemorrhage

e. Respiratory distress

Which of the following would be recommended as a means to diagnose a type I sensitivity? Select all that apply.

a. Skin prick test

b. IgG titers

c. IgM titers

d. IgE titers

e. Histamine levels

Indicate the true statements, and then reword the false statements so they are true.

a. Immunodeficiencies are associated with a decreased cancer risk

b. Type I reactions are mediated by IgG antibodies

c. Autoimmune disorders are not caused by type I hypersensitivities

d. Systemic lupus is mainly mediated by a type III hypersensitivity

e. A person with type 0- blood is called a universal donor

f. Immunotherapies are useful to reduce type II reactions

Which scenario presents the greatest risk for HDN developing?

a. O− mother with O+ fetus

b. A+ mother with O+ fetus

c. B−mother with AB− fetus

d. A−mother with O−fetus

e. AB+ mother with AB−fetus