Skip to main content
Ch. 13 - Immune System Disorders
Norman-McKay- Microbiology: Basic and Clinical Principles 2nd Edition
Norman-McKay2nd EditionMicrobiology: Basic and Clinical PrinciplesISBN: 9780137661619Non è quello che usi tu?Cambia libro di testo
Capitolo 9, Problema 8

Which patient would be the most likely to benefit from desensitization immunotherapy?
a. A person suffering from serum sickness
b. A person at risk for HDN during pregnancy
c. A person with an allergy to pollen
d. A transplant patient
e. An asthmatic patient

Guida verificata passo dopo passo
1
Step 1: Understand what desensitization immunotherapy is. It is a treatment designed to reduce allergic reactions by gradually exposing the patient to increasing amounts of the allergen, helping the immune system become less sensitive over time.
Step 2: Review each patient scenario to identify which condition is related to allergies that can be managed by desensitization immunotherapy.
Step 3: Recognize that serum sickness is an immune complex-mediated hypersensitivity reaction, not typically treated with desensitization.
Step 4: Note that hemolytic disease of the newborn (HDN) involves maternal antibodies attacking fetal red blood cells, which is not addressed by desensitization immunotherapy.
Step 5: Identify that allergies to pollen and asthma are allergic conditions where desensitization immunotherapy is commonly used to reduce symptoms by modifying the immune response.

Risposta video verificata per un problema simile:

Questa soluzione video è stata consigliata dai nostri tutor come utile per risolvere questo problema.
Durata del video:
2m

Concetti chiave

Ecco i concetti essenziali che devi comprendere per rispondere correttamente alla domanda.

Desensitization Immunotherapy

Desensitization immunotherapy, also known as allergy immunotherapy, involves gradually exposing a patient to increasing amounts of an allergen to reduce sensitivity and allergic reactions. It is primarily used to treat allergic conditions such as pollen allergies and some insect venom allergies by modifying the immune response over time.

Allergic Reactions and Hypersensitivity

Allergic reactions are immune responses to harmless substances (allergens) that involve hypersensitivity, often mediated by IgE antibodies. Common symptoms include sneezing, itching, and asthma. Understanding the mechanism of allergies helps identify which patients benefit from therapies like desensitization.
Video consigliato:
01:56
Chemical Reactions

Clinical Indications for Immunotherapy

Immunotherapy is indicated for patients with specific allergic conditions such as pollen allergies or insect venom allergies, but not for conditions like serum sickness, hemolytic disease of the newborn, or transplant rejection. Recognizing the appropriate clinical scenarios ensures effective and safe treatment choices.
Video consigliato:
05:21
Types of Disinfectants
Pratica correlata
Domanda del libro di testo

List the applicable hypersensitivities (type I, II, III, IV) as they relate to the description. Note, more than one type of hypersensitivity may be listed for a given description.

IgG antibodies can mediate type _________________hypersensitivities.

T cells mediate type _________________ hypersensitivities.

Type _________________ hypersensitivities may be generated in response to pharmaceutical drugs.

Type _________________ hypersensitivities may be associated with autoimmunity.

Type _________________ hypersensitivities require a sensitizing exposure.

IgE antibodies can mediate type _________________hypersensitivities.

1505
views
Domanda del libro di testo

Fill in the table.

1829
views
Domanda del libro di testo

Which of the following is (are) true regarding type III hypersensitivity reactions? Select all that apply.

a. They involve IgG

b. They involve IgM

c. They are considered delayed reactions

d. They include autoimmune disorders like multiple sclerosis

e. They are rare compared with type I reactions

1515
views
Domanda del libro di testo

Which of the following is the most likely to lead to graft-versushost disease?

a. An allogeneic bone marrow transplant

b. An allogeneic liver transplant

c. A xenogeneic heart valve transplant

d. An isogenic bone marrow transplant

e. A xenogeneic skin graft

1407
views
Domanda del libro di testo

Which of the following is the most suggestive of an anaphylactic reaction? (NCLEX/HESI/TEAS)

a. Sudden fever

b. A localized rash

c. Nasal congestion

d. Hemorrhage

e. Respiratory distress

1580
views
Domanda del libro di testo

Which scenario presents the greatest risk for HDN developing?

a. O− mother with O+ fetus

b. A+ mother with O+ fetus

c. B−mother with AB− fetus

d. A−mother with O−fetus

e. AB+ mother with AB−fetus

1427
views