In 1884, Elie Metchnikoff observed cells collected around a splinter inserted in a sea star embryo. This was the discovery of
a. blood cells.
b. sea stars.
c. phagocytosis.
d. immunity.
e. none of the above

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Understand the historical context: Elie Metchnikoff is known for his pioneering work in immunology, particularly related to how certain cells respond to foreign bodies.

Recall that Metchnikoff observed cells surrounding a splinter in a sea star embryo, which led to the identification of a specific cellular process.

Recognize that the process observed was the engulfing and digestion of foreign particles by cells, a fundamental immune response.

Identify the term for this process as 'phagocytosis,' which is the mechanism by which certain cells (phagocytes) ingest harmful particles, bacteria, or dead cells.

Conclude that the correct answer corresponds to the discovery of phagocytosis, which is option c.

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Phagocytosis

Phagocytosis is the process by which certain cells, called phagocytes, engulf and digest foreign particles, bacteria, or dead cells. Elie Metchnikoff discovered this mechanism when he observed cells surrounding a splinter in a sea star embryo, highlighting a fundamental immune response.

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Steps of Phagocytosis

Innate Immunity

Innate immunity is the body's first line of defense against pathogens, involving non-specific responses like phagocytosis. Metchnikoff's observation contributed to understanding how organisms naturally protect themselves without prior exposure to a pathogen.

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Introduction to Innate Immunity

Historical Contributions to Immunology

Elie Metchnikoff's work in 1884 was pivotal in immunology, as it identified cellular mechanisms of defense. Recognizing his discovery helps contextualize the development of modern immunology and the role of immune cells in protecting organisms.

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