Which statement best describes the production, storage, and delivery route of bile to the duodenum?

The pancreas synthesizes bile which is then passed to the liver for storage and from there intermittently secreted into the ileum using a system of valves that bypass the duodenum.

Bile is synthesized in the gallbladder epithelium, then travels retrograde to the liver for activation before being secreted into the jejunum through multiple tiny ducts spread along the small intestine.

Bile is produced by hepatocytes in the liver, stored and concentrated in the gallbladder, and delivered to the duodenum via the common bile duct that empties near the pancreatic duct.

Bile originates in the spleen, with the gallbladder filtering and concentrating it before passive diffusion directly across the duodenal wall rather than through a ductal opening.