Which description most accurately summarizes the progressive nature of type 2 diabetes pathophysiology over time?

A sudden autoimmune-mediated loss of all beta cells at disease onset without any preceding insulin resistance, followed by spontaneous recovery of beta-cell function in late stages.

Primary liver disease causing irreversible glycogen overproduction that is independent of insulin action or beta-cell function and never responds to weight loss or exercise.

An inherited absence of glucose transporters in intestinal epithelium causing lifelong hypoglycemia that then flips into hyperglycemia only in the presence of exogenous insulin therapy.

An initial period of peripheral insulin resistance with compensatory hyperinsulinemia that, over time, leads to beta-cell exhaustion and declining insulin secretion, resulting in combined insulin resistance and insulin deficiency.