which-pancreatic-enzyme-is-primarily-responsible-for-activating-other-pancreatic

Question

Which pancreatic enzyme is primarily responsible for activating other pancreatic zymogens (e.g., trypsinogen) in the small intestine?

Accepted Answer

Enteropeptidase (enteropeptidase in the brush border) activates trypsinogen to trypsin, which then activates other zymogens.

Answer

Lipase is the major activator of trypsinogen in the intestinal lumen and therefore initiates protease cascades.

Answer

Pepsin directly activates pancreatic zymogens within the stomach lumen before they enter the small intestine.

Answer

Amylase converts trypsinogen into trypsin by cleaving carbohydrate moieties on the zymogen, allowing activation.