How do the reduction sites of NAD+ and FAD differ in terms of their involvement in metabolic pathways?

NAD+ is involved in dehydrogenation reactions, while FAD is involved in both dehydrogenation and oxidation at the double bond.

NAD+ can only be reduced in anaerobic conditions, unlike FAD.

NAD+ and FAD both reduce glucose directly.

Both NAD+ and FAD are reduced exclusively in the mitochondrial matrix.