Enolate Alkylation and Acylation

24. Enolate Chemistry: Reactions at the Alpha-Carbon / Enolate Alkylation and Acylation / Problema 1

Problema 1

Propose a method for producing the following ketone from the given carboxylic acid using any additional reagents.
cyclopentanecarboxylic acid → methyl cyclopentyl ketone

Reaction scheme showing cyclopentanecarboxylic acid to methyl cyclopentyl ketone using CH3Li.

Reaction scheme converting cyclopentanecarboxylic acid to methyl cyclopentyl ketone using Br2 and Mg.

Reaction scheme showing cyclopentanecarboxylic acid to methyl cyclopentyl ketone using CH3Li and NaOH.

Reaction scheme converting cyclopentanecarboxylic acid to methyl cyclopentyl ketone using Br2, H2O, and Mg.

Propose a method for producing the following ketone from the given carboxylic acid using any additional reagents.cyclopentanecarboxylic acid → methyl cyclopentyl ketone