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Medicinal Chemistry: One-Group/Two-Group C-X Disconnections in Organic Synthesis

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Functional Groups

  • Assigning Degrees to Alkyl Halides
    01:30
  • Why we need functional groups.
    01:49
  • The difference between aldehydes and ketones.
    03:08

Overview of Chemical Reactions

  • Recognizing Substitution Reactions.
    01:34
  • Recognizing Acid-Base Reactions.
    02:43
  • Recognizing Elimination Reactions.
    00:40

Reaction Mechanism

  • How to tell if charged molecules will react as nucleophiles or electrophiles.
    02:39
  • Nucleophile or Electrophile
    01:49
  • How to tell if uncharged molecules will react as nucleophiles or electrophiles.
    02:48

Introduction to Substitution

  • Predict the product
    05:55
  • Nucleophiles and Electrophiles can react in Bronsted-Lowry Reactions.
    05:01
  • Nucleophiles and Electrophiles can react in Substitution Reactions.
    01:47

Leaving Groups

  • The 3 important leaving groups to know.
    07:22

Synthesis of Alcohols Overview

  • Forming alcohols through SN2 reactions.
    01:44
  • Forming alcohols through Acid-Catalyzed Hydration.
    02:02
  • Forming alcohols through Hydroboration-Oxidation.
    01:37

Leaving Group Conversions - Using HX

  • Why do we need to convert Alcohol into a good leaving group?
    02:03
  • Using HX acids via SN2 reaction.
    02:16
  • Using HX acids via SN1 reaction.
    07:20

Leaving Group Conversions - SOCl2 and PBr3

  • Predict the mechanism of PBr3, and draw the final product.
    06:01
  • Learning the mechanism of SOCl2.
    07:18

Synthesis of Amino Acids: Strecker Synthesis

  • Percorso guidato
    Synthesis of Amino Acids: Strecker Synthesis Concept 3
    1:53
  • Percorso guidato
    Synthesis of Amino Acids: Strecker Synthesis Concept 1
    1:39
  • Percorso guidato
    Synthesis of Amino Acids: Strecker Synthesis Example 1
    1:16

Reductive Amination

  • Reductive Amination
    07:12
  • Provide the Major Product
    03:07

Alkane Nomenclature

  • Naming the root chain
    01:02
  • Provide the IUPAC name for the following alkane
    07:08
  • The different parts of an IUPAC name
    03:43