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EKG Fundamentals and Cardiac Cell Physiology: Study Notes for Anatomy & Physiology

스터디 가이드 - 스마트 노트

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Chapter 1: The Basics of EKG

Introduction to EKG

The electrocardiogram (EKG or ECG) is a diagnostic tool that records the electrical activity of the heart over time. It is essential for evaluating cardiac rhythm, conduction, and detecting abnormalities.

  • EKG Function: Detects and records electrical signals that initiate heartbeats, not mechanical function or blood flow.

  • Graphic Representation: The EKG tracing is a graphical representation of voltage changes over time.

  • Standard EKG Paper: Each small square equals 0.04 seconds horizontally; five small squares (one large box) equal 0.20 seconds.

  • Amplitude: One large box vertically equals 0.5 mV; five boxes equal 2.5 mV.

  • Standard Calibration: 1 mV = 10 mm deflection.

Key Terms and Concepts

  • Depolarization: Occurs when the inside of the cell becomes more positive due to sodium influx.

  • Repolarization: Potassium efflux restores the negative resting potential.

  • Resting Membrane Potential: Maintained by the sodium-potassium pump, typically around -90 mV.

  • Baseline (Isoelectric Line): Indicates no detectable electrical activity.

Properties of Cardiac Cells

  • Automaticity: Ability to generate impulses without external stimulation.

  • Conductivity: Ability to transmit impulses.

  • Excitability: Ability to respond to stimuli.

EKG Components and Interpretation

  • P Wave: Represents atrial depolarization.

  • QRS Complex: Represents ventricular depolarization.

  • T Wave: Represents ventricular repolarization.

  • PR Interval: Reflects conduction time from the start of the P wave to the start of the QRS complex (normal: 0.12–0.20 seconds).

  • QT Interval: Covers total ventricular activity (depolarization and repolarization).

  • ST Segment: Represents the period between ventricular depolarization and repolarization.

Electrolyte Effects on EKG

  • Potassium: Abnormalities can flatten or invert T waves.

  • Calcium: Plays a key role in conduction and contraction.

  • Magnesium: Maintains resting membrane potential.

Lead Placement and Function

  • Electrodes: Placed on the body surface to detect electrical potentials.

  • Ground Electrode: Reduces electrical interference.

  • Reference Lead: Lead II is often used for rhythm interpretation.

Table: EKG Waves and Their Cardiac Events

EKG Wave

Cardiac Event

P wave

Atrial depolarization

QRS complex

Ventricular depolarization

T wave

Ventricular repolarization

PR interval

Conduction time from atria to ventricles

QT interval

Total ventricular activity

Types of Cardiac Cells

The heart is composed of three major types of cells: pacemaker cells, electrical conducting cells, and myocardial cells. These cells work together to generate, conduct, and respond to electrical impulses.

  • Pacemaker Cells: Located primarily in the sinoatrial (SA) node, initiate the heartbeat through spontaneous depolarization.

  • Electrical Conducting Cells: Transmit impulses rapidly through the heart's conduction system (e.g., His bundle, Purkinje fibers).

  • Myocardial Cells: Contract in response to impulses but do not initiate them.

Pacemaker Cells and Automaticity

  • SA Node: The primary pacemaker of the heart, sets the rhythm by spontaneous depolarization.

  • Automaticity: Pacemaker cells possess automaticity and generate impulses independently.

  • Conduction System: Includes the AV node, His bundle, bundle branches, and Purkinje fibers.

Resting Membrane Potential and Ion Exchange

  • Resting Potential: Maintained by potassium efflux and sodium-potassium pump ().

  • Depolarization: Sodium influx initiates depolarization; calcium is essential for conduction and contraction.

  • Repolarization: Potassium efflux restores the negative potential.

Table: Cardiac Cell Types and Functions

Cell Type

Main Function

Pacemaker cells

Generate spontaneous impulses (automaticity)

Conducting cells

Transmit impulses rapidly

Myocardial cells

Contract in response to impulses

Key Equations

  • Resting Membrane Potential:

  • EKG Paper Timing:

  • EKG Paper Calibration:

Additional info:

  • EKG interpretation is foundational for understanding cardiac physiology and pathology in Anatomy & Physiology.

  • Electrolyte imbalances (e.g., potassium, calcium) can significantly alter EKG waveforms and cardiac function.

  • Knowledge of cardiac cell types and their properties is essential for interpreting arrhythmias and conduction abnormalities.

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