Question 1

Which layer of the epidermis is responsible for the generation of new keratinocytes and contains tactile epithelial cells associated with touch sensation?

Accepted Answer

Stratum basale

Question 2

A patient presents with a wound that has destroyed the layer of the epidermis where keratinocytes begin to degenerate and keratohyalin is produced. Which layer is most likely affected?

Accepted Answer

Stratum granulosum

Question 3

Which stratum is only found in the thick skin of the fingertips, palms, and soles, and is composed of several layers of clear, dead keratinocytes?

Accepted Answer

Stratum lucidum

Question 4

What is the primary function of the stratum corneum in the epidermis?

Accepted Answer

To protect underlying tissues with multiple layers of dead, keratin-filled cells

Question 5

Which layer of the epidermis contains projections of melanocytes and intraepidermal macrophages, and is composed of eight to ten rows of many-sided keratinocytes?

Accepted Answer

Stratum spinosum

Question 6

During the process of keratinization, in which layer do keratinocytes begin to accumulate large amounts of keratin and lamellar granules?

Accepted Answer

Stratum granulosum

Question 7

A mutation prevents the formation of keratin intermediate filaments in the epidermis. Which two layers would be most directly affected by this defect?

Accepted Answer

Stratum basale and stratum spinosum

Question 8

Which of the following best describes the stratum granulosum?

Accepted Answer

It is composed of three to five rows of flattened keratinocytes in which organelles are beginning to degenerate.

Question 9

If a biopsy reveals a layer of the epidermis with few to 50 or more rows of dead, flat keratinocytes, which layer is being observed?

Accepted Answer

Stratum corneum

Question 10

Which layer of the epidermis is primarily responsible for the skin’s ability to resist water loss due to the presence of lipid-rich lamellar granules?

Accepted Answer

Stratum granulosum

The Epidermal Layers of the Skin: Structure and Function

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