Skip to main content
Ch.24 Lipid Metabolism
McMurry - Fundamentals of General, Organic, and Biological Chemistry 8th Edition
McMurry8th EditionFundamentals of General, Organic, and Biological ChemistryISBN: 9780134015187당신이 사용하는 게 아니라요?교과서 변경
24장, 문제 49a

How many molecules of acetyl-CoA result from complete catabolism of the following compounds?
a. Myristic acid, CH3(CH2)12COOH

검증된 단계별 안내
1
Identify the structure of myristic acid: Myristic acid is a saturated fatty acid with the formula CH₃(CH₂)₁₂COOH. It contains 14 carbon atoms in total (1 from CH₃, 12 from CH₂ groups, and 1 from the carboxylic acid group).
Understand the process of beta-oxidation: Beta-oxidation is the metabolic pathway that breaks down fatty acids into acetyl-CoA molecules. Each cycle of beta-oxidation removes a 2-carbon unit (as acetyl-CoA) from the fatty acid chain.
Determine the number of beta-oxidation cycles: Since myristic acid has 14 carbon atoms, divide the total number of carbons by 2 to determine the number of acetyl-CoA molecules produced. This gives 14 ÷ 2 = 7 acetyl-CoA molecules.
Account for the number of beta-oxidation cycles: The number of beta-oxidation cycles required to completely break down the fatty acid is one less than the number of acetyl-CoA molecules produced. For myristic acid, this would be 7 - 1 = 6 cycles.
Summarize the result: The complete catabolism of myristic acid through beta-oxidation produces 7 molecules of acetyl-CoA. Each acetyl-CoA can then enter the citric acid cycle for further energy production.

비슷한 문제에 대한 검증된 영상 답변:

이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
영상 길이:
1m

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Beta-Oxidation

Beta-oxidation is the metabolic process by which fatty acids are broken down in the mitochondria to generate acetyl-CoA. Each cycle of beta-oxidation shortens the fatty acid chain by two carbon atoms, producing one molecule of acetyl-CoA, along with NADH and FADH2, which are used in the electron transport chain for ATP production.
추천 영상:
가이드 코스
02:32
Characteristics of Beta Particles

Fatty Acid Structure

Fatty acids are long hydrocarbon chains with a carboxylic acid group at one end. The number of carbon atoms in the fatty acid determines how many cycles of beta-oxidation will occur. For example, myristic acid has 14 carbon atoms, which influences the total number of acetyl-CoA molecules produced during its complete catabolism.
추천 영상:
가이드 코스
0:55
Fatty Acids Example 1

Acetyl-CoA Production

Acetyl-CoA is a key metabolic intermediate that enters the citric acid cycle (Krebs cycle) for energy production. Each complete cycle of beta-oxidation of a fatty acid yields one acetyl-CoA molecule, and the total number of acetyl-CoA molecules produced can be calculated by dividing the total number of carbon atoms in the fatty acid by two.
추천 영상:
가이드 코스
01:37
Solubility Product Constant (Ksp) Concept 2