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General Microbiology: Course Syllabus and Topic Overview

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General Microbiology: Course Syllabus and Topic Overview

Course Structure and Organization

This course provides a comprehensive introduction to microbiology, covering the biology of microorganisms, their roles in health and disease, and their applications in biotechnology and the environment. The syllabus outlines the sequence of topics, associated readings, and key assessments.

  • Lecture Schedule: Tuesdays and Thursdays, 10:00-11:20 AM

  • Textbook: Microbiology: An Introduction (14th Edition) by Tortora et al.

  • Assessment: Three exams covering different sets of chapters and topics

  • Additional Materials: Research articles, problem sets, and slides available via Canvas

Course Topics and Weekly Breakdown

The following table summarizes the main topics, dates, and associated textbook readings for each session.

Session

Date

Topic

Reading

1

Sep 2

Course introduction, rules, grading policies; Microbial life: What is a microorganism?

Syllabus, 1

2

Sep 4

Laboratory containment levels

2, Slides

3

Sep 9

Microscopy I

3

4

Sep 11

Microscopy II

3

5

Sep 16

Prokaryotic cell structure and function

4

6

Sep 18

Eukaryotic cell structure and function

4

7

Sep 23

Microbial metabolism I

5

8

Sep 25

Microbial metabolism II

5

9

Sep 30

Microbial growth I

6

10

Oct 2

Microbial growth II

6

11

Oct 7

Exam 1 (Chapters 1-6)

12

Oct 9

Control of microbial growth

7

13

Oct 14

The bacterial genome

8

14

Oct 16

Microbial genetics: replication, transcription, translation

8

15

Oct 21

Biotechnology and recombinant DNA I

9

16

Oct 23

Biotechnology and recombinant DNA II

9, 28

17

Oct 28

Classification of microorganisms I: Domains Prokarya and Archaea

10, 11

18

Oct 30

Classification of microorganisms II: Domain Eukarya

12

20

Nov 4

Exam 2 (Chapters 7-12, 28)

21

Nov 6

Viruses I: Prokaryotic

13

22

Nov 11

Viruses II: Eukaryotic

13

23

Nov 13

Disease and epidemiology

14

24

Nov 18

Pathogenicity

15

25

Nov 20

Immunology I: Innate immunity

16

26

Nov 25

Immunology II: Adaptive immunity and applications of immunology

17, 18, 19

-

Nov 27-30

Thanksgiving Recess

27

Dec 2

Antimicrobial drugs

20

28

Dec 4

Selected microbial diseases

21-26 (sections)

29

Dec 9

Environmental microbiology

27

-

Dec 11, 12

Reading Days

Finals

Dec 16

Exam 3 (Chapters 13-20, 27; Sections of 21-26)

Key Topic Areas

  • Introduction to Microbiology: Definition and scope of microorganisms, course policies.

  • Laboratory Safety: Containment levels and safety protocols in microbiology labs.

  • Microscopy: Principles and applications of light and electron microscopy for studying microbes.

  • Cell Structure and Function: Comparison of prokaryotic and eukaryotic cells, including organelles and cellular processes.

  • Microbial Metabolism: Biochemical pathways, energy production, and metabolic diversity among microbes.

  • Microbial Growth: Factors influencing microbial reproduction and population dynamics.

  • Control of Microbial Growth: Physical and chemical methods for controlling microbial populations.

  • Genetics and Genomics: Structure and function of the bacterial genome, genetic replication, transcription, and translation.

  • Biotechnology: Recombinant DNA technology and its applications in microbiology.

  • Classification of Microorganisms: Taxonomy and phylogeny of prokaryotes, archaea, and eukaryotes.

  • Virology: Structure, replication, and classification of viruses infecting prokaryotes and eukaryotes.

  • Disease and Epidemiology: Mechanisms of disease transmission, epidemiological methods, and outbreak investigation.

  • Pathogenicity: Microbial mechanisms of pathogenicity and host-pathogen interactions.

  • Immunology: Innate and adaptive immune responses, immunological memory, and applications such as vaccination.

  • Antimicrobial Drugs: Mechanisms of action, resistance, and clinical applications of antibiotics and other antimicrobials.

  • Microbial Diseases: Overview of selected infectious diseases caused by bacteria, viruses, fungi, and parasites.

  • Environmental Microbiology: Roles of microbes in ecosystems, biogeochemical cycles, and environmental biotechnology.

Assessment and Exams

  • Exam 1: Covers foundational topics (Chapters 1-6)

  • Exam 2: Focuses on microbial genetics, biotechnology, and classification (Chapters 7-12, 28)

  • Exam 3: Emphasizes virology, immunology, antimicrobial drugs, diseases, and environmental microbiology (Chapters 13-20, 27; selected sections of 21-26)

Additional info:

  • Students are expected to supplement textbook readings with materials provided on Canvas, including research articles and problem sets.

  • Laboratory safety and containment are critical for all practical sessions.

  • Thanksgiving Recess and Reading Days are scheduled to allow for review and preparation for final assessments.

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