Discuss hemoglobin relative to its chemical structure, its function, and the color changes it undergoes during loading and unloading of oxygen.

Cancer patients being treated with chemotherapeutic drugs designed to destroy rapidly dividing cells are monitored closely for changes in their red and white blood counts. Why so?

Define hemostasis

List the three major phases of coagulation. Explain what initiates each phase and what the phase accomplishes

In what general way do the intrinsic and extrinsic mechanisms of clotting differ?

Which ion is essential to virtually all stages of coagulation?

How is clot overgrowth usually prevented?

List two conditions that may lead to unnecessary (and undesirable) clot formation.

Alan Forsythe, a middle-aged college professor from Boston, is in the Swiss Alps studying astronomy during his sabbatical leave. He has been there for two days and plans to stay the entire year. However, he notices that he is short of breath when he walks up steps and tires easily with any physical activity. His symptoms gradually disappear, and he feels fine after less than a month. Upon returning to the United States, he has a complete physical exam and is told that his erythrocyte count is higher than normal.

a. Attempt to explain this finding.

b. Will his RBC count remain at this higher-than-normal level? Why or why not?

Amanda Healy, a young woman with severe vaginal bleeding, is admitted to the emergency room. She is three months pregnant, and the physician is concerned about the volume of blood she is losing.

What type of transfusion will probably be given to this patient?

Which blood tests will be performed before starting the transfusion?

How can poor nutrition lead to anemia?