In glycolysis (per one molecule of glucose), what are the net products under aerobic conditions before pyruvate enters the mitochondrion?
A
2 pyruvate, 2 ATP (net), 2 NADH, and 2
B
2 lactate, 2 ATP (net), and 2 NADH
C
2 acetyl-CoA, 2 ATP (net), and 2 NADH
D
2 pyruvate, 4 ATP (net), and 2 NADH
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1
Identify the starting molecule and the pathway: Glycolysis starts with one molecule of glucose and breaks it down into smaller molecules in the cytoplasm.
Recall the main products of glycolysis per glucose molecule: Glycolysis produces pyruvate, ATP, and NADH before any further aerobic or anaerobic processing.
Calculate ATP yield: Glycolysis uses 2 ATP molecules in the initial steps and produces 4 ATP molecules later, so the net ATP is calculated as 4 (produced) minus 2 (used).
Determine the number of NADH molecules produced: During glycolysis, 2 molecules of NAD+ are reduced to 2 NADH molecules as glucose is oxidized.
Summarize the net products before pyruvate enters the mitochondrion under aerobic conditions: These include 2 pyruvate molecules, net 2 ATP, and 2 NADH molecules. Water (H2O) is also produced as a byproduct in one of the steps.