Why is it crucial to know whether a hormone is lipid-based or not in experimental design?

Because all hormones function identically, making their type irrelevant.

Because lipid-based hormones cannot be used in any therapeutic interventions.

Because non-lipid hormones are always more potent than lipid-based hormones.

Because lipid-based hormones can diffuse through membranes, affecting intracellular targets, unlike non-lipid hormones.