in-the-catalytic-triad-what-role-does-histidine-57-play-in-the-mechanism-of-chym

Question

In the catalytic triad, what role does histidine 57 play in the mechanism of chymotrypsin?

Accepted Answer

Histidine 57 acts as a base, acquiring a hydrogen from serine 195.

Answer

Histidine 57 acts as an acid, donating a hydrogen to serine 195.

Answer

Histidine 57 enhances the nucleophilic ability of aspartate 102.

Answer

Histidine 57 stabilizes the transition state by forming covalent bonds.