a-peptides-serine-residue-has-a-pka-of-130-in-a-standard-environment-if-the-micr

Question

A peptide's serine residue has a pKa of 13.0 in a standard environment. If the microenvironment shifts the pKa to 12.0, how does this affect the charge at pH 7.4?

Accepted Answer

The serine residue remains neutral.

Answer

The serine residue becomes positively charged.

Answer

The serine residue becomes zwitterionic.

Answer

The serine residue becomes negatively charged.