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Foundations of General Biology: Characteristics of Life, Biological Organization, and Chemistry of Life

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Characteristics of Life

Five Fundamental Characteristics of Living Organisms

  • Cells: All organisms are made up of membrane-bound cells.

  • Replication: All organisms are capable of reproduction.

  • Information: All organisms process hereditary information encoded in genes as well as information from the environment.

  • Energy: All organisms acquire and use energy to stay alive.

  • Evolution: Populations of organisms are continually evolving.

Hierarchy of Biological Organization

  • Biosphere: All environments on Earth.

  • Ecosystem: All living and nonliving things in a particular area.

  • Community: All organisms in an ecosystem.

  • Population: All individuals of a species in a particular area.

  • Organism: An individual living thing.

  • Organ and Organ System: Specialized body parts made up of tissues.

  • Tissue: A group of similar cells.

  • Cell: Life's fundamental unit of structure and function.

  • Organelle: A structural component of a cell.

  • Molecule: A chemical structure consisting of atoms.

The Central Dogma of Molecular Biology

Flow of Genetic Information

  • DNA codes for ribonucleic acid (RNA), which codes for proteins.

  • RNA: Molecules that carry out specialized functions in cells. Messenger RNA (mRNA) is read to make proteins (transcription).

  • Proteins:

    • Crucial to tasks required by cells.

    • Form structural components and promote chemical reactions.

    • Proteins determine physical traits of organisms.

  • Base Pairing: A pairs with T, G pairs with C. Permits DNA copying and preserves genetic information.

  • End Result: An organism's traits are determined by the flow of genetic information from DNA to RNA to protein.

Theories in Biology

  • Cell Theory:

    • All organisms are made up of cells.

    • All cells come from preexisting cells.

Cells: Eukaryotes and Prokaryotes

  • Eukaryotes: Organisms with membrane-bound organelles, including a nucleus.

    • Domain Eukarya: Includes all eukaryotic organisms.

    • Three Kingdoms:

      • Plants: Produce their own food by photosynthesis.

      • Fungi: Absorb nutrients.

      • Animals: Ingest their food.

  • Prokaryotes: Organisms without a nucleus or membrane-bound organelles.

    • Usually single-celled organisms.

    • Includes Bacteria and Archaea.

Key Terminology

  • Biology: The scientific study of life, encompassing all living organisms and their interactions.

  • Cell: The smallest and most fundamental unit of life.

  • Organism: Any individual form of life.

  • Multicellular: Organisms composed of many cells that often specialize and work together.

  • Microscope: Instrument used to visualize cells and other small structures.

  • Adaptations: Traits that enhance an organism's ability to survive and reproduce.

  • Alleles: Different versions of a gene.

  • Abiotic: Non-living chemical and physical parts of the environment.

  • Acclimatization: The process by which an organism adjusts to changes in its environment over time.

Atoms and Subatomic Particles

Structure of the Atom

  • Atoms are composed of protons, neutrons, and electrons.

Subatomic Particle

Electric Charge

Atomic Mass Unit

Location

Proton

+1

1

Nucleus

Neutron

0

1

Nucleus

Electron

-1

0

Orbiting Nucleus

Atomic Number and Mass

  • Atomic Number: Number of protons in the nucleus. Determines the element.

  • Mass Number: Sum of protons and neutrons.

  • Atomic Mass: Average mass of all isotopes of an element.

Electron Orbitals

  • Electrons occupy orbitals around the nucleus.

  • Shells closer to the nucleus are lower in energy; outer shells are higher in energy and more reactive.

  • Valence Electrons: Electrons in the outermost shell, important for chemical bonding.

  • 1st shell holds up to 2 electrons; 2nd shell up to 8 electrons.

Isotopes

  • Atoms of the same element with the same number of protons but different numbers of neutrons.

  • Isotopes have different mass numbers.

  • Radioactive Isotopes: Unstable isotopes that break down and emit energy.

    • Half-life: Time it takes for half of the radioactive atoms in a sample to decay.

    • Used in medicine and radiometric dating of fossils.

Chemical Bonds

Types of Bonds

  • Covalent Bonds: Atoms share electrons.

    • Nonpolar Covalent: Equal sharing of electrons.

    • Polar Covalent: Unequal sharing, leading to partial charges.

  • Electronegativity: Measure of an atom's attraction to electrons (scale: 0-4).

  • Noncovalent Bonds: No sharing of electrons.

    • Ionic Bonds: Attraction between oppositely charged ions (cations and anions).

    • Hydrogen Bonds: Weak attraction between a hydrogen atom and an electronegative atom (F, O, N).

    • Van der Waals Interactions: Weak attractions due to transient charges.

Properties of Water

  • Polarity: Water is a polar molecule with partial positive and negative charges.

  • Hydrogen Bonding: Water molecules form hydrogen bonds with each other.

  • Emergent Properties:

    1. Cohesion: Water molecules stick together (surface tension).

    2. Adhesion: Water molecules stick to other substances.

    3. High Specific Heat: Water resists temperature change.

    4. High Heat of Vaporization: Energy required to convert water from liquid to gas.

    5. Low Density of Ice: Ice floats on liquid water.

    6. Universal Solvent: Water dissolves many substances.

      • Hydrophilic: Water-loving (ions, polar molecules).

      • Hydrophobic: Water-fearing (nonpolar molecules).

Water in Acid-Base Reactions

  • Water dissociates:

  • Acids: Donate protons (), increase proton concentration.

  • Bases: Accept protons (), decrease proton concentration.

  • Concentrations:

    • Mole: molecules.

    • Molecular Weight: Sum of atomic weights.

    • Molarity (M): Moles per liter of solution.

Example: The Central Dogma in Action

  • Example: The gene for hemoglobin in DNA is transcribed into mRNA, which is then translated into the hemoglobin protein, determining the trait of oxygen transport in red blood cells.

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