a-cell-is-unable-to-release-certain-proteins-into-the-extracellular-space-which-

Question

A cell is unable to release certain proteins into the extracellular space. Which defect in GPI anchor processing could explain this?

Accepted Answer

Failure to add the GPI anchor to the protein, preventing its attachment to the plasma membrane.

Answer

Defective ER retention signal, causing the protein to be retained in the ER.

Answer

Incorrect glycosylation of the protein, leading to misfolding.

Answer

Inability to cleave the ER signal sequence, preventing protein translocation.