How does the presence of calcium ions affect the interaction between actin and myosin?

Calcium ions bind directly to myosin, enhancing its binding to actin.

Calcium ions inhibit ATP hydrolysis, stopping muscle contraction.

Calcium ions bind to troponin, causing tropomyosin to move and expose actin binding sites for myosin.

Calcium ions bind to actin, preventing myosin from attaching.