Question 1

Which of the following is a forbidden transfer of information according to the central dogma of molecular biology?

Accepted Answer

Protein $$\rightarrow$$ RNA

Question 2

If the G + C content of the RNA of an E. coli cell is 30%, what is the most reasonable assumption about the G + C content of the cell's DNA?

Accepted Answer

50%

Question 3

Which enzyme is primarily responsible for transcribing DNA into RNA in prokaryotes?

Accepted Answer

RNA polymerase

Question 4

The fidelity of the initiation of transcription in prokaryotes is determined by which factor?

Accepted Answer

Sigma factor

Question 5

What is the primary function of a promoter in gene expression?

Accepted Answer

RNA core polymerase recognition

Question 6

The eukaryotic equivalent of the prokaryotic Pribnow box is known as the:

Accepted Answer

Goldstein-Hogness (TATA) box

Question 7

The coding strand of DNA is complementary to:

Accepted Answer

The template strand

Question 8

How many ribosomal RNA segments do prokaryotes and eukaryotes have, respectively?

Accepted Answer

Three, three

Question 9

Which post-transcriptional modification is found in eukaryotic mRNAs?

Accepted Answer

5' cap

Question 10

During self-splicing, RNA is acting like a:

Accepted Answer

Ribozyme

Question 11

If an RNA molecule has the sequence 5' GCAAUGCAA 3', what is the sequence of the DNA template strand that was transcribed?

Accepted Answer

3'-CGTTACGTT-5'

Question 12

Which of the following best describes RNA editing?

Accepted Answer

Many bases are changed

Question 13

The sequence of amino acids in a protein is referred to as its:

Accepted Answer

Primary structure

Question 14

How many aminoacyl-tRNA synthetases are typically found in a cell?

Accepted Answer

20

Question 15

The first amino acid synthesized is at which end of the protein?

Accepted Answer

Amino

Question 16

The first amino acid incorporated into E. coli proteins is:

Accepted Answer

N-formyl methionine

Question 17

The enzyme that creates peptide bonds at the ribosome is called:

Accepted Answer

Transferase

Question 18

Termination of translation requires:

Accepted Answer

Release factor

Question 19

Which of the following best explains why a mutation in the stop codon of a gene can result in a protein with an extra 50 amino acids at the end?

Accepted Answer

The stop codon was mutated

Question 20

Which region(s) of a gene are NOT found within the mature mRNA transcript?

Accepted Answer

Promoter region

Genetics Exam 3 Study Guide: Chapters 8–11 (Transcription, Translation, Chromosome Structure, and Mutation)

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