Question 1

Which probability law is applied when calculating the chance of inheriting two independent genes located on different chromosomes?

Accepted Answer

Multiplication rule

Question 2

In a pedigree, two unaffected parents have a child with a genetic disorder. What is the most likely inheritance pattern?

Accepted Answer

Autosomal recessive

Question 3

If a trait appears in every generation and affects both males and females equally, which inheritance mode is most likely?

Accepted Answer

Autosomal dominant

Question 4

What is the probability that a child will have the genotype AaBbCc from a cross between two AaBbCc parents?

Accepted Answer

Question 5

A pedigree shows a trait that is only passed from father to son and never appears in females. What is the most likely inheritance pattern?

Accepted Answer

Y-linked

Question 6

In a monohybrid cross (Aa x Aa), what is the probability of obtaining a dominant phenotype in the offspring?

Accepted Answer

$$\frac{3}{4}$$

Question 7

Which rule would you use to calculate the probability of a child being either a boy or a girl in a single birth?

Accepted Answer

Addition rule

Question 8

A pedigree shows that affected fathers do not pass the trait to their sons, and males are more often affected than females. What is the most likely inheritance pattern?

Accepted Answer

X-linked recessive

Question 9

If a heterozygote produces gametes, what is the probability that a gamete will carry either the dominant or the recessive allele?

Accepted Answer

$$1$$

Question 10

Which of the following is NOT a question to ask when determining inheritance mode from a pedigree?

Accepted Answer

Is the trait always lethal?

Question 11

A pedigree shows that all daughters of an affected father have the disease, but none of his sons do. What is the most likely inheritance pattern?

Accepted Answer

X-linked dominant

Question 12

In a family, two heterozygous carriers for an autosomal recessive disorder have four children. What is the expected probability that at least one child will have the disorder?

Accepted Answer

$$1 - (\frac{3}{4})^4$

Question 13

Which Mendelian law is associated with the multiplication rule in probability calculations?

Accepted Answer

Law of independent assortment

Question 14

A pedigree shows that the trait is rare, skips generations, and is more common in males. Which inheritance mode is most likely?

Accepted Answer

X-linked recessive

Question 15

If a trait is observed in both males and females but only appears when both parents are unaffected, what is the most likely inheritance pattern?

Accepted Answer

Autosomal recessive

Question 16

What is the probability of having three boys in three consecutive births?

Accepted Answer

$$\frac{1}{8}$$

Question 17

Which inheritance mode is suggested if a trait is only found in males and is passed from father to all sons?

Accepted Answer

Y-linked

Question 18

In a cross between two AaBbCc individuals, what is the probability of an offspring being homozygous recessive for all three genes?

Accepted Answer

$$\frac{1}{64}$$

Question 19

Which probability law is used when calculating the chance of a gamete carrying either allele from a heterozygote?

Accepted Answer

Addition rule

Question 20

A pedigree shows that the trait appears in every generation and all daughters of affected fathers are affected, but sons are not. What is the most likely inheritance pattern?

Accepted Answer

X-linked dominant

Pedigree Analysis and Probability in Genetic Inheritance

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