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Ch. 2 - Mitosis and Meiosis
Klug - Concepts of Genetics 12th Edition
Klug12th EditionConcepts of GeneticsISBN: 9780135564776당신이 사용하는 게 아니라요?교과서 변경
2장, 문제 30

Consider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis.
Assume that each gamete resulting from Problem 29 fuses, in fertilization, with a normal haploid gamete. What combinations will result? What percentage of zygotes will be diploid, containing one paternal and one maternal member of each chromosome pair?

검증된 단계별 안내
1
First, understand the chromosome setup: the diploid cell has three pairs of chromosomes (AA, BB, CC), each with a maternal (e.g., A^{m}) and paternal (e.g., A^{p}) homolog. Before mitosis or meiosis, each chromosome replicates, forming two sister chromatids per chromosome, which remain attached at the centromere.
For mitosis, illustrate that after replication, each chromosome consists of two identical sister chromatids (e.g., A^{m} with two identical chromatids). During mitosis, sister chromatids separate, so each daughter cell receives one chromatid from each chromosome pair, maintaining the diploid number and identical genetic content.
For meiosis, start by showing synapsis during prophase I, where homologous chromosomes (e.g., A^{m} and A^{p}) pair up tightly, forming tetrads of four chromatids. Crossing over may occur here, exchanging genetic material between non-sister chromatids.
After meiosis I, homologous chromosomes separate into two cells, each still with sister chromatids attached. Then, during meiosis II, sister chromatids separate, resulting in four haploid gametes, each containing one chromatid from each chromosome pair (either maternal or paternal origin, possibly recombinant due to crossing over).
For fertilization, consider that each gamete from meiosis fuses with a normal haploid gamete (with one chromatid from each chromosome). To find the combinations of zygotes, combine the chromatids from both gametes. The percentage of diploid zygotes containing one paternal and one maternal member of each chromosome pair depends on the assortment and recombination events; calculate this by considering independent assortment probabilities and crossing over outcomes.

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이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
영상 길이:
1m

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Chromosome Structure and Replication

Chromosomes consist of two sister chromatids joined at a centromere after DNA replication. In a diploid cell, each chromosome pair has one maternal and one paternal homolog. Replication doubles chromatids, preparing the cell for division, and is essential for understanding chromatid pairing during mitosis and meiosis.
추천 영상:
가이드 코스
07:10
Chromosome Structure

Mitosis vs. Meiosis

Mitosis produces two genetically identical diploid daughter cells by separating sister chromatids, maintaining chromosome number. Meiosis involves two divisions, reducing chromosome number by half and producing haploid gametes with recombined chromatids due to synapsis and crossing over between homologous chromosomes.
추천 영상:
가이드 코스
05:30
Meiosis Overview

Fertilization and Zygote Formation

Fertilization fuses two haploid gametes, restoring diploidy in the zygote. The genetic combination depends on the gametes' chromosome composition, including whether chromatids are maternal or paternal. Understanding this helps predict the percentage of zygotes with one maternal and one paternal chromosome from each pair.
추천 영상:
가이드 코스
04:06
Formation of Plant Gametes
관련 실천
교과서 질문

A species of cereal rye (Secale cereale) has a chromosome number of 14, while a species of Canadian wild rye (Elymus canadensis) has a chromosome number of 28. Sterile hybrids can be produced by crossing Secale with Elymus.

What would be the expected chromosome number in the somatic cells of the hybrids?

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교과서 질문

Consider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis.

Are there any possible combinations present during prophase of meiosis II other than those that you drew in Problem 26? If so, draw them.

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교과서 질문

An interesting procedure has been applied for assessing the chromosomal balance of potential secondary oocytes for use in human in vitro fertilization. Using fluorescence in situ hybridization (FISH), Kuliev and Verlinsky (2004) were able to identify individual chromosomes in first polar bodies and thereby infer the chromosomal makeup of 'sister' oocytes. Assume that when examining a first polar body you saw that it had one copy (dyad) of each chromosome but two dyads of chromosome 21. What would you expect to be the chromosomal 21 complement in the secondary oocyte? What consequences are likely in the resulting zygote, if the secondary oocyte was fertilized?

386
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교과서 질문

Consider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis.

Assume that during meiosis I none of the C chromosomes disjoin at metaphase, but they separate into dyads (instead of monads) during meiosis II. How would this change the alignments that you constructed during the anaphase stages in meiosis I and II? Draw them.

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교과서 질문

Consider a diploid cell that contains three pairs of chromosomes designated AA, BB, and CC. Each pair contains a maternal and a paternal member (e.g., Am and Ap). Using these designations, demonstrate your understanding of mitosis and meiosis by drawing chromatid combinations as requested. Be sure to indicate when chromatids are paired as a result of replication and/or synapsis.

Draw all possible combinations of chromatids during the early phases of anaphase in meiosis II.

507
views
교과서 질문

A species of cereal rye (Secale cereale) has a chromosome number of 14, while a species of Canadian wild rye (Elymus canadensis) has a chromosome number of 28. Sterile hybrids can be produced by crossing Secale with Elymus.

Given that none of the chromosomes pair at meiosis I in the sterile hybrid (Hang and Franckowlak, 1984), speculate on the anaphase I separation patterns of these chromosomes.

1171
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