Identify the true statement from the following statements on factor/s affecting the spontaneity of a reaction.

The enthalpy of a reaction is the sole determining factor as to whether the reaction will be spontaneous or nonspontaneous.

The change in enthalpy or heat and the entropy change of the reaction both affect the spontaneity of a reaction.

Only the change in the degree of disorder determines the spontaneity of a reaction.

Neither the enthalpy change nor the entropy change affects the spontaneity of a reaction since the number of molecules interacting determines spontaneity.